BDBM50485674 CHEMBL2153639

SMILES O=C(Nc1ccccc1)Nc1cccc(c1)C(=O)Nc1cnc2[nH]ncc2c1

InChI Key InChIKey=FUBCCLOWKPWWOU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50485674   

TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50485674(CHEMBL2153639)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of B-Raf V600E mutant in human Malme-3M cells assessed as ERK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50485674(CHEMBL2153639)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of full length B-Raf V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed