BDBM50485669 (+)-14-Hydroxymethylxestoquinone::CHEMBL2153503

SMILES C[C@@]12CCCc3coc(c13)C(=O)c1cc3C(=O)C(CO)=CC(=O)c3cc21

InChI Key InChIKey=JBYAETKFTXZVJF-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50485669   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
University of Mississippi

Curated by ChEMBL

LigandBDBM50485669((+)-14-Hydroxymethylxestoquinone | CHEMBL2153503)Copy SMILESCopy InChI

Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of 1,10-phenanthroline-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/30/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
University of Mississippi

Curated by ChEMBL

LigandBDBM50485669((+)-14-Hydroxymethylxestoquinone | CHEMBL2153503)Copy SMILESCopy InChI

Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/30/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL