BDBM50485606 CHEBI:63925::Latanoprost acid

SMILES c1ccc(cc1)CC[C@@H](CC[C@H]2[C@@H](C[C@@H]([C@@H]2C/C=C\CCCC(=O)O)O)O)O

InChI Key InChIKey=HNPFPERDNWXAGS-UHFFFAOYSA-N

Data  1 KI  1 EC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50485606   

TargetProstaglandin F2-alpha receptor(Mouse)
Theravance

Curated by ChEMBL
LigandPNGBDBM50485606(CHEBI:63925 | Latanoprost acid)
Affinity DataEC50:  6.30nMAssay Description:Agonist activity at FP receptor in mouse 3T3 fibroblast cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSolute carrier organic anion transporter family member 2A1(Human)
Yamanashi Medical University

Curated by ChEMBL
LigandPNGBDBM50485606(CHEBI:63925 | Latanoprost acid)
Affinity DataKi:  149nMAssay Description:TP_TRANSPORTER: inhibition of PGE1 uptake (PGE1: 0.0004 uM) in PGT-expressing HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed