BDBM50485288 CHEMBL2046980

SMILES [H][C@]1(CCCN1C(=O)COc1c(C)cccc1C)[C@H](O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)COc1c(C)cccc1C

InChI Key InChIKey=KVJAYJAKAUAELO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50485288   

TargetProtease(Human immunodeficiency virus type 1)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50485288(CHEMBL2046980)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of Human immunodeficiency virus 1 protease using Abz-Thr-Ile-Nle-Phe(p-NO2)-Gln-Arg-NH2 as substrate by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50485288(CHEMBL2046980)
Affinity DataIC50: 0.00150nMAssay Description:Inhibition of HIV1 3B protease activity in human H9 cells using Abz-Thr-Ile-Nle-Phe(p-NO2)-Gln-Arg-NH2 as substrate after 40 mins by spectrophotometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed