BDBM50485285 CHEMBL1233644

SMILES CC(C)[C@@H](C(=O)N[C@@H](Cc1ccccc1)[C@@H]([C@H]([C@@H]2CCCN2C(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3c[nH]c4c3cccc4)NC(=O)C)O)O)NC(=O)[C@H](Cc5c[nH]c6c5cccc6)NC(=O)C

InChI Key InChIKey=BDIYLIYACVEIHS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50485285   

TargetProtease(Human immunodeficiency virus type 1)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50485285(CHEMBL1233644)
Affinity DataIC50: 5nMAssay Description:Inhibition of HIV1 3B protease activity in human H9 cells using Abz-Thr-Ile-Nle-Phe(p-NO2)-Gln-Arg-NH2 as substrate after 40 mins by spectrophotometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50485285(CHEMBL1233644)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Human immunodeficiency virus 1 protease using Abz-Thr-Ile-Nle-Phe(p-NO2)-Gln-Arg-NH2 as substrate by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed