BDBM50485076 CHEMBL2023402::US20250099433, Compound 1-(R)

SMILES C[C@@](CCN1C=CC(=CC1=O)c2ccc(cc2F)OC)(C(=O)NO)S(=O)(=O)C

InChI Key InChIKey=DNVUWHWBCMGQLU-UHFFFAOYSA-N

Data  1 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50485076   

TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50485076(CHEMBL2023402 | US20250099433, Compound 1-(R))
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxC expressed in Escherichia coli using UDP-3-O-N-acetylglucosamine substrate measured after 30 mins by mass sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
The State University of New York

US Patent
LigandPNGBDBM50485076(CHEMBL2023402 | US20250099433, Compound 1-(R))
Affinity DataKi:  0.0150nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2025
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)