BDBM50484730 CHEMBL1949981

SMILES CN(C)c1ccc(Cl)c(Nc2nc(cs2)-c2sc(NC(=O)c3ccc([19F])cc3)nc2C)c1

InChI Key InChIKey=WTFCITBRZGJGOO-TYXRKMBKSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484730   

TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50484730(CHEMBL1949981)
Affinity DataEC50:  1.40E+3nMAssay Description:Corrector activity at human CFTR delta F508 mutant expressed in rat FRT cells coexpressing fluorescent protein YFP-H148Q/1152L by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed