BDBM50484656 CHEMBL1940227

SMILES COc1ccc(cc1OC)S(=O)(=O)N(Cc1ccc2OC(C)(C)C=Cc2n1)C1CCC1

InChI Key InChIKey=CQGIUFASDNXPRB-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50484656   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
Georgia State University

Curated by ChEMBL

LigandBDBM50484656(CHEMBL1940227)Copy SMILESCopy InChI

Affinity DataIC50: 280nMAssay Description:Inhibition of HIF1 in human LN229 cells after 1 hr preincubation under hypoxic condition measured after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
8/29/2020
Entry Details Article
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TargetHistone acetyltransferase p300/Hypoxia-inducible factor 1-alpha(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50484656(CHEMBL1940227)Copy SMILESCopy InChI

Affinity DataIC50: 280nMAssay Description:Inhibition of HIF-1alpha (unknown origin)/p300 (unknown origin) protein-protein interactionMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL