BDBM50484105 CHEMBL1812408

SMILES CCCCCCCCn1c2ccccc2c2ccc(OC3=C(O)C(Cc4ccc5OCOc5c4)N(Cc4ccccc4)C3=O)cc12

InChI Key InChIKey=ATPDEEMKNFGJNJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50484105   

TargetPresenilin-1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50484105(CHEMBL1812408)
Affinity DataIC50: 3.10E+4nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta38 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50484105(CHEMBL1812408)
Affinity DataIC50: 3.20E+4nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta40 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50484105(CHEMBL1812408)
Affinity DataIC50: 2.40E+4nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta42 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed