BDBM50483918 CHEMBL1779734

SMILES CCc1[nH]c2nc(C)nc(-c3cc(OC)c(Cl)cc3Cl)c2c1C#N

InChI Key InChIKey=JBONTTFKXPZARB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50483918   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483918(CHEMBL1779734)
Affinity DataIC50: 500nMAssay Description:Inhibition of HSP90 in human H1299 cells assessed as degradation of Akt protein after 24 hrs by luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed