BDBM50483558 CHEMBL1689182

SMILES [#6]-[#6]-[#6]-c1cc(=O)oc2c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c(-[#6](=O)-[#6@H](-[#6])-[#6]-[#6])c(-[#8])c12

InChI Key InChIKey=GVDWYUNRGJRZSF-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50483558   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
University of Mississippi

Curated by ChEMBL

LigandBDBM50483558(CHEMBL1689182)Copy SMILESCopy InChI

Affinity DataIC50: 9.96E+3nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells expressing pGL3 construct after 16 hrs by cell-based luciferase reporter assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoChEBI
PC cidPC sidSimilars

In Depth
Date in BDB:
8/29/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
University of Mississippi

Curated by ChEMBL

LigandBDBM50483558(CHEMBL1689182)Copy SMILESCopy InChI

Affinity DataIC50: 8.21E+3nMAssay Description:Inhibition of 1,10-phenanthrolin-induced HIF1 activation in human T47D cells expressing pGL3 construct after 16 hrs by cell-based luciferase reporter...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoChEBI
PC cidPC sidSimilars

In Depth
Date in BDB:
8/29/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL