BDBM50482518 CHEMBL1214382

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc4nc(N)c(=O)[nH]c34)c3ccccc23)n(n1)-c1ccccc1

InChI Key InChIKey=GZLUSKKVLZNIIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50482518   

TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50482518(CHEMBL1214382)
Affinity DataIC50: 405nMAssay Description:Inhibition of B-Raf V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50482518(CHEMBL1214382)
Affinity DataIC50: 36nMAssay Description:Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed