BDBM50482311 CHEMBL1171516

SMILES Cc1cc(cc(C)c1Oc1nc(NC2CCN(CC2)c2ccccc2)ncc1Br)C#N

InChI Key InChIKey=RJOOKMMKGISVIY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50482311   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482311(CHEMBL1171516)
Affinity DataIC50: 192nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482311(CHEMBL1171516)
Affinity DataIC50: 334nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482311(CHEMBL1171516)
Affinity DataIC50: 112nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482311(CHEMBL1171516)
Affinity DataIC50: 192nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482311(CHEMBL1171516)
Affinity DataIC50: 112nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482311(CHEMBL1171516)
Affinity DataIC50: 334nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase Y188L mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed