BDBM50482310 CHEMBL1170006

SMILES Cc1cc(cc(C)c1Oc1ccnc(NC2CCN(Cc3ccc(cc3Cl)S(N)(=O)=O)CC2)n1)C#N

InChI Key InChIKey=WNAQTQAFQRRPDX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50482310   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482310(CHEMBL1170006)
Affinity DataIC50: 84nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482310(CHEMBL1170006)
Affinity DataIC50: 105nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482310(CHEMBL1170006)
Affinity DataIC50: 25nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed