BDBM50482299 CHEMBL1170387

SMILES Cc1cc(cc(C)c1Oc1ccnc(NC2CCN(Cc3ccc(cc3Cl)S(C)(=O)=O)CC2)n1)C#N

InChI Key InChIKey=AETWZMHUXWRPAH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50482299   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482299(CHEMBL1170387)
Affinity DataIC50: 263nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482299(CHEMBL1170387)
Affinity DataIC50: 22nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482299(CHEMBL1170387)
Affinity DataIC50: 30nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed