BDBM50482196 CHEMBL1083283

SMILES C[C@H]1N([C@@H](C)C(=O)c2[nH]ncc12)S(=O)(=O)c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=RSEQEACXQZGJOR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50482196   

TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50482196(CHEMBL1083283)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of gamma-secretase-mediated notch cleavage in human SNC cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed