BDBM50482172 CHEMBL1083121

SMILES FC(F)(F)c1ccc(cc1)S(=O)(=O)N1C(C2CC2)c2cn[nH]c2C(=O)C11CCCC1

InChI Key InChIKey=FEVSHGTXBDMNIX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50482172   

TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50482172(CHEMBL1083121)
Affinity DataIC50: 235nMAssay Description:Inhibition of gamma-secretase-mediated notch cleavage in human SNC cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed