BDBM50481818 CHEMBL5277493

SMILES CON1c2ccccc2C2(C=C(O)C(=O)N3\C(=C\c4cnc[nH]4)C(=O)NC123)C(C)(C)C=C

InChI Key InChIKey=JTJJJLSLKZFEPJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50481818   

TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli (strain K12))
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50481818(CHEMBL5277493)
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of Escherichia coli DH5alpha FabI in the presence of NADH using crotonyl CoA as substrate by measuring NADH consumption rateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain MRSA252))
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50481818(CHEMBL5277493)
Affinity DataIC50: 4.01E+4nMAssay Description:Inhibition of Staphylococcus aureus FabI assessed as inhibition at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed