BDBM50481591 CHEMBL5289891

SMILES Fc1cccc(c1)-c1nc2occn2c1-c1ccnc(NCCCNS(=O)(=O)c2ccccc2)n1

InChI Key InChIKey=DMEBBSDHOMWAOU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50481591   

TargetSerine/threonine-protein kinase B-raf(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50481591(CHEMBL5289891)
Affinity DataIC50: 172nMAssay Description:Inhibition of wild type B-Raf (unknown origin) by radiometric protein kinase-reaction biology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50481591(CHEMBL5289891)
Affinity DataIC50: 92nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin) by radiometric protein kinase-reaction biology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed