BDBM50481483 CHEMBL589285

SMILES COc1cc(cc(OC)c1OC)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1

InChI Key InChIKey=RFHHKLHLLXMGOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50481483   

TargetVoltage-dependent L-type calcium channel subunit beta-1(Human)
Neuromed Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50481483(CHEMBL589285)
Affinity DataIC50: 510nMAssay Description:Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481483(CHEMBL589285)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed