BDBM50481477 CHEMBL599402

SMILES Clc1ccc(cc1)[C@H](N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1

InChI Key InChIKey=AOQSRDPSBXFFQW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50481477   

LigandPNGBDBM50481477(CHEMBL599402)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of L type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells in presence of -100 mV holding potential by whole-cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit beta-1(Human)
Neuromed Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50481477(CHEMBL599402)
Affinity DataIC50: 50nMAssay Description:Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481477(CHEMBL599402)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed