BDBM50481447 CHEMBL598598

SMILES Clc1ccc(cc1)C(N1CCN(CC(=O)N(c2ccccc2)c2ccccc2)CC1)c1ccccc1

InChI Key InChIKey=CEXBUHRJNQKOBZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50481447   

TargetVoltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Human)
Neuromed Pharmaceuticals

Curated by ChEMBL

LigandBDBM50481447(CHEMBL598598)Copy SMILESCopy InChI

Affinity DataIC50: 110nMAssay Description:Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch c...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/27/2020
Entry Details Article
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TargetVoltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1(Human)
Neuromed Pharmaceuticals

Curated by ChEMBL

LigandBDBM50481447(CHEMBL598598)Copy SMILESCopy InChI

Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR methodMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/27/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL