BDBM50481444 CHEMBL5290203

SMILES COc1cc(ccc1Cl)-c1nn(cc1-c1ccncc1)-c1ccc(NC(=O)CN2CCOCC2)cc1

InChI Key InChIKey=SVKARUKFVYVPHK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50481444   

TargetSerine/threonine-protein kinase B-raf(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50481444(CHEMBL5290203)
Affinity DataIC50: 536nMAssay Description:Inhibition of wild type B-Raf (unknown origin) by hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50481444(CHEMBL5290203)
Affinity DataIC50: 3nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin) by hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed