BDBM50481437 CHEMBL5284834

SMILES FC(F)(F)c1cc(NC(=O)Nc2ccc(Oc3ccc(cc3)C(=O)c3ncc[nH]3)cc2)ccc1Cl

InChI Key InChIKey=DSJMYOCWLYQGRW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50481437   

TargetSerine/threonine-protein kinase B-raf(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50481437(CHEMBL5284834)
Affinity DataIC50: 86nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50481437(CHEMBL5284834)
Affinity DataIC50: 134nMAssay Description:Inhibition of wild type B-Raf (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed