BDBM50481253 N,N''-Disalicylalethylenediamine::N,N'-DISALICYLALETHYLENEDIAMINE

SMILES Oc1ccccc1\C=N\CC\N=C\c1ccccc1O

InChI Key InChIKey=VEUMANXWQDHAJV-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50481253   

Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Escherichia coli)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50481253(N,N''-Disalicylalethylenediamine | N,N'-DISALICYLA...)
Affinity DataIC50: 1.86E+5nMAssay Description:Inhibition of Escherichia coli Beta-ketoacyl-ACP synthase III expressed in Escherichia coli BL21 (DE3) by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50481253(N,N''-Disalicylalethylenediamine | N,N'-DISALICYLA...)
Affinity DataKi:  280nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50481253(N,N''-Disalicylalethylenediamine | N,N'-DISALICYLA...)
Affinity DataKi:  1.72E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50481253(N,N''-Disalicylalethylenediamine | N,N'-DISALICYLA...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50481253(N,N''-Disalicylalethylenediamine | N,N'-DISALICYLA...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed