BDBM50480870 CHEMBL571713

SMILES COc1cc(NC(=O)CCc2ccc(OCc3ccc(Cl)cc3)c(OC)c2)c(OC)cc1Cl

InChI Key InChIKey=NDZJQDZKTAJEHO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50480870   

TargetDNA-binding transcriptional activator DevR/DosR(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Indian Institute of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50480870(CHEMBL571713)
Affinity DataIC50: 2.48E+5nMAssay Description:Inhibition of DevR region-dependent Rv3134c promoter activity in Mycobacterium tuberculosis H37Rv after 48 hrs by GFP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetDNA-binding transcriptional activator DevR/DosR(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Indian Institute of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50480870(CHEMBL571713)
Affinity DataIC50: 2.95E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis phosphorylated DevR binding to fdxA promoter DNA after 10 mins by EMSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed