BDBM50480588 CHEMBL538442::K-Strophanthoside

SMILES [H][C@@]12CC[C@]3(O)C[C@H](CC[C@]3(C=O)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@]21O)C1=CC(=O)OC1)O[C@H]1C[C@H](OC)[C@H](O[C@@H]2O[C@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](C)O1

InChI Key InChIKey=GILGYKHFZXQALF-UHFFFAOYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50480588   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
Saic-Frederick

Curated by ChEMBL

LigandBDBM50480588(K-Strophanthoside | CHEMBL538442)Copy SMILESCopy InChI

Affinity DataEC50:  40nMAssay Description:Inhibition of HIF1 activation in human U251 cells stably transfected in pGL2-TK-HRE plasmid under hypoxic condition after 16 to 24 hrs by luciferase ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
8/27/2020
Entry Details Article
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