BDBM50480572 CHEMBL563346

SMILES COc1c(C)cnc(CN2[C@@H](C)C(=O)Nc3c(Cl)nc(N)nc23)c1C

InChI Key InChIKey=UOUTZRIJTVPXFA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50480572   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Poniard Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50480572(CHEMBL563346)
Affinity DataIC50: 430nMAssay Description:Inhibition of HSP90 in human SKBR3 cells assessed as induction of Her2 degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed