BDBM50480348 CHEMBL5271182

SMILES CN1CCN(CCNc2nccc(n2)C2(CC2)C(=O)Nc2cc(ccc2C)C(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)CC1

InChI Key InChIKey=RJXMEVOEGYJKTE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50480348   

TargetSerine/threonine-protein kinase B-raf(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50480348(CHEMBL5271182)
Affinity DataIC50: 13nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50480348(CHEMBL5271182)
Affinity DataIC50: 20nMAssay Description:Inhibition of wild type B-Raf (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed