BDBM50478462 7,12-O,O''-dimethyl-N-methylcoclaurine::CHEMBL452500

SMILES COc1ccc(CC2N(C)CCc3cc(OC)c(OC)cc23)cc1

InChI Key InChIKey=LZJWNVLTWYMMDJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50478462   

TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rat)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50478462(7,12-O,O''-dimethyl-N-methylcoclaurine | CHEMBL452...)
Affinity DataKi:  4.17E+3nMAssay Description:Displacement of [3H]diltiazem from benzodiazepine binding site of L-type calcium channel in Wistar rat cerebral cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50478462(7,12-O,O''-dimethyl-N-methylcoclaurine | CHEMBL452...)
Affinity DataKi:  7.94E+3nMAssay Description:Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed