BDBM50477916 CHEMBL252645

SMILES C[C@H](CCCn1nccn1)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=CLMFHVQNEUWLFS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50477916   

TargetPresenilin-1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50477916(CHEMBL252645)
Affinity DataIC50: 12nMAssay Description:Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed