BDBM504777 US11040966, Example 5.1::[(S)-2-Methyl-2-(4-methyl-1H-benzoimidazol-2-yl)-pyrrolidin-1-yl]-(2-methyl-5-phenyl-thiazol-4-yl)-methanone

SMILES Cc1nc(C(=O)N2CCC[C@@]2(C)c2nc3c(C)cccc3[nH]2)c(s1)-c1ccccc1

InChI Key InChIKey=WLNITWARANCOHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 504777   

TargetOrexin/Hypocretin receptor type 1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM504777([(S)-2-Methyl-2-(4-methyl-1H-benzoimidazol-2-yl)-p...)
Affinity DataIC50: 26nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
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TargetOrexin receptor type 2(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM504777([(S)-2-Methyl-2-(4-methyl-1H-benzoimidazol-2-yl)-p...)
Affinity DataIC50: 13nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
Go to US Patent