BDBM50477333 CHEMBL396692

SMILES CCCc1ccc(cc1)S(=O)(=O)n1c2ccccc2c2ccc(OCC(O)=O)cc12

InChI Key InChIKey=RBBNVYWJKJXKAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50477333   

TargetPresenilin-1(Human)
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477333(CHEMBL396692)
Affinity DataIC50: 3.80E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta42 formation LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477333(CHEMBL396692)
Affinity DataIC50: 4.00E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta-40 formation LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed