BDBM50477159 CHEMBL391735

SMILES CCC(=O)c1ccc(F)c([C@@H]2C[C@@H]2NC(=O)Nc2ccc(cn2)C#N)c1O

InChI Key InChIKey=NKPHEWJJTGPRSL-UHFFFAOYSA-N

Data  8 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50477159   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50477159(CHEMBL391735)
Affinity DataKd:  0.627nMAssay Description:Binding affinity to HIV1 reverse transcriptase Y181C mutant at 5 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50477159(CHEMBL391735)
Affinity DataKd:  0.790nMAssay Description:Binding affinity to HIV1 reverse transcriptase Y181C mutant at 15 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50477159(CHEMBL391735)
Affinity DataKd:  3.49nMAssay Description:Binding affinity to HIV1 reverse transcriptase K103N mutant at 35 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50477159(CHEMBL391735)
Affinity DataKd:  1nMAssay Description:Binding affinity to HIV1 reverse transcriptase K103N mutant at 15 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50477159(CHEMBL391735)
Affinity DataKd:  0.596nMAssay Description:Binding affinity to HIV1 reverse transcriptase K103N mutant at 5 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50477159(CHEMBL391735)
Affinity DataKd:  2.90nMAssay Description:Binding affinity to HIV1 reverse transcriptase Y181C mutant at 35 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50477159(CHEMBL391735)
Affinity DataKd:  4.90nMAssay Description:Binding affinity to HIV1 reverse transcriptase K103N mutant at 25 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50477159(CHEMBL391735)
Affinity DataKd:  1.5nMAssay Description:Binding affinity to HIV1 reverse transcriptase Y181C mutant at 25 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed