BDBM50476819 CHEMBL235780

SMILES OCCONC(=O)c1c[nH]c(=O)cc1Nc1ccc(Br)cc1F

InChI Key InChIKey=NIZMUWJLIMKOIH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50476819   

TargetDual specificity mitogen-activated protein kinase kinase 1/2(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50476819(CHEMBL235780)
Affinity DataIC50: 3.63E+3nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50476819(CHEMBL235780)
Affinity DataIC50: 120nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed