BDBM50476815 CHEMBL396631

SMILES NC(=O)c1c[nH]c(=O)cc1Nc1ccc(I)cc1F

InChI Key InChIKey=HALXYXINRHRFCA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50476815   

TargetDual specificity mitogen-activated protein kinase kinase 1/2(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50476815(CHEMBL396631)
Affinity DataIC50: 100nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50476815(CHEMBL396631)
Affinity DataIC50: 630nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed