BDBM50475680 Arecaidine Propargyl Ester

SMILES CN1CCC=C(C1)C(=O)OCC#C

InChI Key InChIKey=SPHRJZBOFYIKMC-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50475680   

TargetMuscarinic acetylcholine receptor M2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50475680(Arecaidine Propargyl Ester)
Affinity DataKi:  87nMAssay Description:Binding affinity to cloned human muscarinic M2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50475680(Arecaidine Propargyl Ester)
Affinity DataKi:  851nMAssay Description:Binding affinity to cloned human muscarinic M3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50475680(Arecaidine Propargyl Ester)
Affinity DataKi:  933nMAssay Description:Binding affinity to cloned human muscarinic M5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50475680(Arecaidine Propargyl Ester)
Affinity DataKi:  977nMAssay Description:Binding affinity to cloned human muscarinic M4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50475680(Arecaidine Propargyl Ester)
Affinity DataKi:  1.23E+3nMAssay Description:Binding affinity to cloned human muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor DM1(Fruit fly)
University of California

Curated by ChEMBL
LigandPNGBDBM50475680(Arecaidine Propargyl Ester)
Affinity DataKi:  4.49E+3nMAssay Description:Displacement of [3H]QNB from Drosophila melanogaster mAChR by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor DM1(Fruit fly)
University of California

Curated by ChEMBL
LigandPNGBDBM50475680(Arecaidine Propargyl Ester)
Affinity DataKi:  5.20E+3nMAssay Description:Displacement of [3H]AF-DX 384 from Drosophila melanogaster mAChR by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed