BDBM50475226 CHEMBL190727

SMILES CC(C)(C(=O)Nc1ccc(cc1)C(=O)NO)c1ccccc1

InChI Key InChIKey=JIABWGUGVPHCNE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50475226   

TargetHistone deacetylase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50475226(CHEMBL190727)
Affinity DataIC50: 98nMAssay Description:In vitro inhibitory concentration against histone deacetylase of DU-145 prostate cell nuclear extract as deacetylation of biotinylated [3H]-acetyl hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50475226(CHEMBL190727)
Affinity DataIC50: 218nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before Ac-Leu- Gly-Lys(Ac)-AMC substrate addition and measured after 90 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed