BDBM50474701 CHEMBL147830

SMILES Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)c1ccc(Cl)cc1

InChI Key InChIKey=ISTLEDHRAMPSGK-UHFFFAOYSA-N

Data  5 KI  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50474701   

TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50474701(CHEMBL147830)
Affinity DataKd:  1.90nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50474701(CHEMBL147830)
Affinity DataKd:  1.90nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetN-acetyltransferase Eis(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50474701(CHEMBL147830)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis Eis assessed as Eis-mediated kanamycin acetylation preincubated for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50474701(CHEMBL147830)
Affinity DataKi:  1.70nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50474701(CHEMBL147830)
Affinity DataKi:  1.70nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Florida A and M University

Curated by ChEMBL
LigandPNGBDBM50474701(CHEMBL147830)
Affinity DataKi:  7.34nMAssay Description:Displacement of [3H]7-OH-DPAT from human Dopamine receptor D3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Florida A and M University

Curated by ChEMBL
LigandPNGBDBM50474701(CHEMBL147830)
Affinity DataKi:  7.59nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50474701(CHEMBL147830)
Affinity DataKi:  7.81nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed