BDBM50473771 CHEMBL93574

SMILES C[S+]([O-])c1ccc(CSc2nc(O)c(-c3ccc(F)cc3)c(n2)-c2ccncc2)cc1

InChI Key InChIKey=AJNRSMOOOOIKIW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50473771   

TargetMitogen-activated protein kinase 11/12/13/14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50473771(CHEMBL93574)
Affinity DataIC50: 2.55E+4nMAssay Description:Inhibition of p38 MAP kinase related interleukin (IL1-beta (cytokine) release from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50473771(CHEMBL93574)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of p38 MAP kinase related TNF-alpha release from peripheral blood mononuclear cells (PBMC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50473771(CHEMBL93574)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of p38 MAP kinase related interleukin (IL1-beta (cytokine) release from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50473771(CHEMBL93574)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of p38 MAP kinase related TNF-alpha release from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed