BDBM50472569 CHEMBL440854

SMILES FC1(CNCc2cccc(n2)-n2cccn2)CCN(CC1)C(=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=RIGJMEXZMQNBKZ-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50472569   

Target5-hydroxytryptamine receptor 1A(Human)
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50472569(CHEMBL440854)
Affinity DataEC50:  28nMAssay Description:In vitro effective concentration required to inhibit forskolin-stimulated cAMP levels in HA7 cells expressing human 5-HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50472569(CHEMBL440854)
Affinity DataKi:  1.70nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat cortex using [3H]8-OH-DPAT as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed