BDBM50472568 CHEMBL42393

SMILES Fc1ccc(cc1Cl)C(=O)N1CCC(F)(CNCc2cccc(n2)-c2ccco2)CC1

InChI Key InChIKey=CCUGUSMEABKPDB-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50472568   

Target5-hydroxytryptamine receptor 1A(Human)
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50472568(CHEMBL42393)
Affinity DataEC50:  3.5nMAssay Description:In vitro effective concentration required to inhibit forskolin-stimulated cAMP levels in HA7 cells expressing human 5-HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50472568(CHEMBL42393)
Affinity DataKi:  0.282nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat cortex using [3H]8-OH-DPAT as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50472568(CHEMBL42393)
Affinity DataKi:  759nMAssay Description:Binding affinity towards Alpha-1 adrenergic receptor using prazosin as a radioligand in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50472568(CHEMBL42393)
Affinity DataKi:  2.24E+3nMAssay Description:Binding affinity towards Dopamine receptor D2 in rat striatum using YM-09151-2 as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed