BDBM50472220 Dolastatin 15::Dolostatin 15

SMILES COC1=CC(=O)N([C@H]1Cc1ccccc1)C(=O)[C@@H](OC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C)C(C)C)C(C)C

InChI Key InChIKey=LQKSHSFQQRCAFW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50472220   

TargetSimilar to alpha-tubulin isoform 1(Bovine)
Upr 9023 Cnrs

Curated by ChEMBL
LigandPNGBDBM50472220(Dolastatin 15 | Dolostatin 15)
Affinity DataIC50: 1.70E+4nMAssay Description:In vitro inhibition of tubulin polymerization measured as turbidity formed by centrifugationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed