BDBM50470578 CHEMBL4282111

SMILES Nc1ccccc1NC(=O)CCCCCCC(=O)NO

InChI Key InChIKey=AENKNAKODODQJV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50470578   

LigandPNGBDBM50470578(CHEMBL4282111)
Affinity DataIC50: 21nMAssay Description:Inhibition of His6-tagged HDAC3/SMRT (395 to 489 residues) (unknown origin) co-expressed in baculovirus infected sf9 cells using (FAM)-labeled acetyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470578(CHEMBL4282111)
Affinity DataIC50: 67nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor-de-Lys as substrate at 50 uM for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470578(CHEMBL4282111)
Affinity DataIC50: 101nMAssay Description:Inhibition of human recombinant HDAC2 using Fluor-de-Lys as substrate at 50 uM for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470578(CHEMBL4282111)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of human recombinant HDAC6 using Fluor-de-Lys as substrate at 50 uM for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470578(CHEMBL4282111)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant HDAC3 using Fluor-de-Lys as substrate at 50 uM for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470578(CHEMBL4282111)
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant HDAC10 using Fluor-de-Lys as substrate at 50 uM for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed