BDBM50470576 CHEMBL4294949

SMILES Nc1ccccc1NC(=O)c1ccc(CN2CC(=C)c3ccccc3C2=O)cc1

InChI Key InChIKey=GTLTXEIKQVWSRF-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50470576   

TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50: 16nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50: 220nMAssay Description:Inhibition of HDAC3 (unknown origin) using peptide substrate measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human HDAC4 using fluorescently-labeled acetylated histone peptide as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC6 using fluorescently-labeled acetylated histone peptide as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human HDAC3 using fluorescently-labeled acetylated histone peptide as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human HDAC2 using fluorescently-labeled acetylated histone peptide as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC8 using fluorescently-labeled acetylated histone peptide as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of recombinant human HDAC7 using fluorescently-labeled acetylated histone peptide as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of recombinant human HDAC1 using fluorescently-labeled acetylated histone peptide as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human recombinant HDAC3 at 0.5 uM using Fluor-de-Lys substrate incubated for 30 mins by fluorometric activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed