BDBM50470567 CHEMBL4283263

SMILES Nc1ccccc1NC(=O)c1cnccn1

InChI Key InChIKey=LMWPVSNHKACEKW-UHFFFAOYSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50470567   

TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470567(CHEMBL4283263)
Affinity DataIC50: 289nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470567(CHEMBL4283263)
Affinity DataIC50: 289nMAssay Description:Inhibition of recombinant human full length HDAC3 using (S)-6-acetamido-2-(2-((S)-2-acetamido-4-methylpentanamido)acetamido)-N-(4-methyl-2-oxo-2H-chr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470567(CHEMBL4283263)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in Sf9 insect cells using (S)-6-acetamido-2-(2-((S)-2-acetamido-4-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470567(CHEMBL4283263)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC2 expressed in Sf9 insect cells using (S)-6-acetamido-2-(2-((S)-2-acetamido-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470567(CHEMBL4283263)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human full length C-terminal His/FALG-tagged HDAC1 expressed in Sf9 insect cells using (S)-6-acetamido-2-(2-((S)-2-acetamid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470567(CHEMBL4283263)
Affinity DataIC50: 289nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470567(CHEMBL4283263)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of recombinant human HDAC1 using fluorescent as substrate measured for 15 mins by fluorescence based microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470567(CHEMBL4283263)
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of recombinant human HDAC2 using fluorescent as substrate measured for 30 mins by fluorescence based microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470567(CHEMBL4283263)
Affinity DataIC50: 566nMAssay Description:Inhibition of recombinant human HDAC3 using fluorescent as substrate measured for 15 mins by fluorescence based microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Birla Institute of Technology and Science-Pilani Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50470567(CHEMBL4283263)
Affinity DataIC50: 2.85E+3nMAssay Description:Inhibition of recombinant human HDAC8 using fluorescent as substrate measured for 10 mins by fluorescence based microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470567(CHEMBL4283263)
Affinity DataIC50: 3.42E+3nMAssay Description:Inhibition of recombinant human HDAC6 using fluorescent as substrate measured for 10 mins by fluorescence based microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470567(CHEMBL4283263)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470567(CHEMBL4283263)
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470567(CHEMBL4283263)
Affinity DataIC50: 566nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Birla Institute of Technology and Science-Pilani Hyderabad Campus

Curated by ChEMBL
LigandPNGBDBM50470567(CHEMBL4283263)
Affinity DataIC50: 2.85E+4nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470567(CHEMBL4283263)
Affinity DataIC50: 3.42E+4nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed