BDBM50470497 CHEMBL4292012

SMILES CNc1ncc(C(=O)NCc2ccc(cc2)C(F)(F)F)c2nc(nn12)-c1ccco1

InChI Key InChIKey=HATKLAXIQZSKPC-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50470497   

TargetAdenosine receptor A3(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50470497(CHEMBL4292012)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]HEMADO from human adenosine A3 receptor expressed in CHO cell membranes after 3 hrs by micro beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50470497(CHEMBL4292012)
Affinity DataKi:  15nMAssay Description:Binding affinity to human adenosine A3A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50470497(CHEMBL4292012)
Affinity DataKi:  2.95E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cell membranes after 3 hrs by micro beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50470497(CHEMBL4292012)
Affinity DataKi:  3.85E+3nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cell membranes after 3 hrs by micro beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50470497(CHEMBL4292012)
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cell membranes assessed as inhibition of NECA-stimulated adenylyl cyclase activi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed