BDBM50470454 CHEMBL4282040

SMILES Oc1cccc(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Cl)cc1

InChI Key InChIKey=XSAQFVZJTOJQCI-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50470454   

TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50470454(CHEMBL4282040)
Affinity DataIC50: 840nMAssay Description:Inhibition of recombinant human C-terminal His-tagged MAGL expressed in Escherichia coli using 4-NPA as substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50470454(CHEMBL4282040)
Affinity DataIC50: 840nMAssay Description:Inhibition of human recombinant MAGL using 4-NPA as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50470454(CHEMBL4282040)
Affinity DataIC50: 840nMAssay Description:Inhibition of human recombinant MAGL using 4-NPA substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50470454(CHEMBL4282040)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of FAAH (unknown origin) incubated for 30 mins using AMC arachidonoylamide substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50470454(CHEMBL4282040)
Affinity DataIC50: 845nMAssay Description:Inhibition of human recombinant MAGL using 4-NPA as substrate by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50470454(CHEMBL4282040)
Affinity DataKi:  650nMAssay Description:Competitive inhibition of human recombinant MAGL using 4-NPA substrate incubated for 30 mins by Michaelis-Menten kinetics analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed