BDBM50470421 CHEMBL4293423

SMILES CCCCCCCCCCCCC\C(=N/O)c1cc(ccc1O)-c1ccc(O)c(F)c1

InChI Key InChIKey=HDOKJCNJHOXSDX-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50470421   

TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50470421(CHEMBL4293423)
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant human C-terminal His-tagged MAGL expressed in Escherichia coli using 4-NPA as substrate pretreated with substrate 15 mins i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50470421(CHEMBL4293423)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 expressed crude membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50470421(CHEMBL4293423)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human ABHD6 expressed in HEK293 cells using 2-OG as substrate pretreated for 30 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50470421(CHEMBL4293423)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate pretreated for 30 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50470421(CHEMBL4293423)
Affinity DataIC50: 680nMAssay Description:Inhibition of recombinant human C-terminal His-tagged MAGL expressed in Escherichia coli using 4-NPA as substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50470421(CHEMBL4293423)
Affinity DataIC50: 4.10E+3nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 expressed crude membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50470421(CHEMBL4293423)
Affinity DataIC50: 680nMAssay Description:Inhibition of recombinant human C-terminal His-tagged MAGL expressed in Escherichia coli using 4-NPA as substrate pretreated with substrate 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetLysophosphatidylserine lipase ABHD12(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50470421(CHEMBL4293423)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human ABHD12 expressed in HEK293 cells using 2-OG as substrate pretreated for 30 mins followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed