BDBM504698 US11066396, Example 124::tert-butyl (S)-1- (2,3-difluoro-4-(5- (trifluoromethyl)- 1,2,4-oxadiazol-3- yl)phenyl)-5- oxopyrrolidine-2- carboxylate
SMILES CC(C)(C)OC(=O)[C@@H]1CCC(=O)N1c1ccc(-c2noc(n2)C(F)(F)F)c(F)c1F
InChI Key InChIKey=IZXFYHXMNLMKGL-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 504698
Affinity DataIC50: 16nMAssay Description:HDAC1 and 6 reagents: FLAG-tagged HDACs 1 and 6 were prepared in-house by protein expression in HEK293F cells followed by anti-FLAG affinity purifica...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:HDAC1 and 6 reagents: FLAG-tagged HDACs 1 and 6 were prepared in-house by protein expression in HEK293F cells followed by anti-FLAG affinity purifica...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+3nMAssay Description:HDAC8 reagents: HDAC8 was purchased from Enzo Life Sciences [catalog #BML-SE145]. Assays were performed with buffer containing 20 mM HEPES, pH 8.0 [B...More data for this Ligand-Target Pair